Searching for Oxidized Low-Density Lipoproteins <i>In Vivo</i>
نویسندگان
چکیده
منابع مشابه
Oxidized Low Density Lipoproteins
The direct vasoactive effects of native and oxidatively modified low density lipoproteins as well as their effects on endothelium-dependent relaxations to 5-hydroxytryptamine were studied in isolated rings of pig right coronary artery. Slowly developing contractions were caused by native low density lipoproteins (100 gg protein/ml). The contractions were more pronounced in the absence than in t...
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Platelets and lipoproteins play a crucial role in atherogenesis, in part by their ability to modulate inflammation and oxidative stress. While oxidized low density lipoproteins (OxLDL) play a central role in the development of this disease, high density lipoproteins (HDL) represent an atheroprotective factor of utmost importance. As platelet function is remarkably sensitive to the influence of ...
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Oxidized low density lipoproteins (oxLDL) formed in vivo induce a humoral immune response. Oxidative modification of LDL renders it immunogenic and a heterogeneous population of specific anti-oxLDL antibodies is produced. These antibodies could represent a biological marker of oxidative stress and serve as markers of atherosclerosis. Autoantibodies against oxLDL (oLAb) have been detected in hum...
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a Department of Biomedical Engineering and Division of Cardiovascular Medicine, University of Southern California, School of Engineering and School of Medicine, Los Angeles, CA 90089-1451, USA b Department of Electrical Engineering, Electro-Physics, University of Southern California, School of Engineering, Los Angeles, CA 90089-1451, USA c Department of Molecular Pharmacology and Toxicology and...
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ژورنال
عنوان ژورنال: Journal of Clinical Biochemistry and Nutrition
سال: 2005
ISSN: 0912-0009,1880-5086
DOI: 10.3164/jcbn.37.1